Research
Zinc Picolinate
9 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Double-blind, placebo-controlled trial of zinc picolinate for taste disorders.
Double-blind, placebo-controlled trial of zinc picolinate in 73 patients with idiopathic zinc-deficiency taste disorder. No significant difference in subjective symptoms or whole-mouth taste sensation between groups, but the zinc group showed better improvement in taste using the filter paper disk method and higher serum zinc levels.
Antioxidant effect of zinc picolinate in patients with chronic obstructive pulmonary disease.
RCT investigating the effects of zinc picolinate supplementation on oxidative stress and pulmonary function in 30 COPD patients and 15 healthy controls. Zinc supplementation increased SOD and zinc levels but did not significantly change MDA, CAT levels, or pulmonary function tests. Suggests zinc may improve oxidant-antioxidant balance in COPD.
[Therapeutic efficacy of zinc picolinate in patients with taste disorders].
Double-blind study assessing the therapeutic efficacy of zinc picolinate in patients with zinc-deficient and idiopathic taste disorders. Significant differences were found between zinc picolinate and placebo groups in improvement grades and serum zinc concentration, but not in total subjective recovery.
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
In vitro study combining zinc picolinate with flavonoids to inhibit respiratory RNA viruses. The combination showed a 50-95% decrease in genome replication levels of viruses like HCoV-OC43, IAV, and hMPV, without affecting cell viability.
Effects of magnesium picolinate, zinc picolinate, and selenomethionine co-supplementation on reproductive hormones, and glucose and lipid metabolism-related protein expressions in male rats fed a high-fat diet.
The study examined the effects of magnesium picolinate, zinc picolinate, and selenomethionine, alone or in combination, on blood metabolites, oxidative enzymes, reproductive hormones, and metabolism-related protein expressions in male Wistar rats on a high-fat diet. The combination of all three supplements provided the greatest positive responses in reversing negative effects induced by the high-fat diet.
Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans.
A double-blind four-period crossover trial in 15 healthy volunteers compared the absorption of zinc picolinate, zinc citrate, and zinc gluconate. Zinc picolinate significantly increased zinc levels in hair, urine, and erythrocytes, suggesting improved absorption compared to zinc citrate, zinc gluconate, and placebo.
Zinc Picolinate Mitigates Colonic Inflammation and Enhances Barrier Function in a Rat Model of Ulcerative Colitis.
The study investigated the effects of zinc picolinate supplementation in a rat model of acetic acid-induced colitis. Zinc picolinate pretreatment attenuated colonic damage, oxidative stress, and inflammation while enhancing antioxidant status and tight junction proteins, suggesting protective effects against experimental colitis.
Zinc picolinate in the prevention of leiomyoma in Japanese quail.
Animal study investigating zinc picolinate supplementation on leiomyoma development and oxidative stress markers in Japanese quails. Zinc supplementation reduced tumor size and oxidative stress markers, but did not affect the number of leiomyomas.
Protective role of zinc picolinate on cisplatin-induced nephrotoxicity in rats.
The study investigated the protective role of zinc picolinate on cisplatin-induced nephrotoxicity in rats. Zinc picolinate treatment significantly reduced markers of oxidative stress and inflammation in the kidney, suggesting its potential as a preventive agent against renal injury caused by cisplatin.