Research
Triphala
21 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review.
Systematic review of 13 studies involving 13,906 patients examining the role of diet, nutritional supplements, and micronutrients in seborrheic dermatitis. Triphala improved patient satisfaction and decreased scalp sebum levels over 8 weeks. The review highlights the need for further studies on zinc, vitamin D, and vitamin E supplementation.
Comparative anti-plaque and anti-gingivitis efficiency of Triphala versus chlorhexidine mouthwashes in children: a systematic review and meta-analysis.
Systematic review and meta-analysis comparing the efficacy of Triphala and chlorhexidine mouthwashes in reducing plaque formation and gingivitis in children. Five studies were included, and no significant difference was found between the two mouthwash groups in reducing gingivitis and plaque accumulation.
Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review.
Systematic review of 12 RCTs with 749 patients assessing triphala's effects on lipid profile, blood glucose, and anthropometric parameters. Triphala significantly reduced LDL-cholesterol, total cholesterol, triglycerides, body weight, BMI, and waist circumference in certain populations. It also decreased fasting blood glucose in diabetic patients. No serious adverse events were reported.
Effect of triphala mouthrinse on plaque and gingival inflammation: A systematic review and meta-analysis of randomized controlled trials.
Systematic review and meta-analysis of RCTs assessing the efficacy of triphala mouthwash compared to chlorhexidine mouthwash in treating plaque-induced gingivitis. Triphala mouthwash was found to be significantly effective in improving gingival inflammatory parameters, showing equal clinical efficacy to chlorhexidine.
Determination of chemical composition and investigation of potential of triphala powder in hypercholesterolemia in men in controlled randomized trial.
This randomized controlled trial investigated the effect of Triphala powder on hypercholesterolemia in men. Encapsulated 400 mg and 600 mg doses were given to treatment groups, and lipid profile parameters were measured over 10 weeks. Triphala powder showed a significant reduction in lipid profile parameters, indicating a positive effect on heart health.
Caries-affected dentin disinfection using Triphala, Indocyanine green, and Potassium Titanyl Phosphate laser and their effect on adhesive bond strength.
The study assessed the impact of different cavity sterilization methods, including Triphala, on adhesive bond strength in caries-affected dentin. Triphala and ozone water showed better bond integrity compared to other methods, suggesting their potential use as cavity disinfectants.
Effect of oral administration of Triphala, a polyphenol-rich prebiotic, on scalp sebum in patients with scalp seborrhea a randomized clinical trial.
RCT of 80 patients with scalp seborrhea comparing 1g Triphala to placebo over 8 weeks. Triphala significantly reduced scalp sebum levels and increased treatment satisfaction compared to placebo.
Evaluation of antibacterial efficacy of Triphala toothwipes on oral Streptococcus mutans count in intellectually disabled children.
RCT evaluating the antibacterial efficacy of Triphala toothwipes on oral Streptococcus mutans counts in 27 intellectually disabled children. The Triphala group showed a statistically significant reduction of S. mutans after 48 hours and 7 days compared to placebo. Both groups showed a significant reduction in dental plaque.
Modulatory Effects of Triphala and Manjistha Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study.
A 4-week double-blind, randomized, placebo-controlled pilot study evaluated the effects of triphala and manjistha supplementation on gut microbiota in 31 healthy subjects. The study found that while responses were highly personalized, both treatments showed a trend toward decreased Firmicutes to Bacteroidetes ratio and reduced relative abundance of Rikenellaceae.
"Nature cures:" An alternative herbal formulation as a denture cleanser.
RCT evaluating the antifungal properties of triphala churna compared to chlorhexidine gluconate on denture base material in 60 denture wearers. Triphala showed more efficacy as an antifungal than chlorhexidine.
Efficacy of triphala extract and chlorhexidine mouth rinse against plaque accumulation and gingival inflammation among female undergraduates: A randomized controlled trial.
A double-blinded RCT among 60 female undergraduates compared the efficacy of 0.6% triphala extract and 0.12% chlorhexidine mouth rinse against plaque accumulation and gingival inflammation. Both triphala and chlorhexidine significantly reduced plaque and gingival scores compared to the control group, with no significant difference between the two treatments.
Triphala, a New Herbal Mouthwash for the Treatment of Gingivitis: A Randomized Controlled Clinical Trial.
RCT evaluating the efficacy of triphala (TRP) mouthwash in reducing plaque and gingivitis in 90 individuals with chronic generalized gingivitis. TRP mouthwash showed comparable improvements in inflammatory parameters to chlorhexidine mouthwash, suggesting its potential as a therapeutic agent for gingivitis.
Antiplaque and antigingivitis efficacy of triphala and chlorhexidine mouthrinse among schoolchildren - a cross-over, double-blind, randomised controlled trial.
Double-blind, crossover RCT comparing the effects of 10% triphala and 0.2% chlorhexidine mouthrinses on dental plaque and gingivitis in 120 schoolchildren. Both triphala and chlorhexidine significantly reduced plaque and gingival index scores compared to the negative control, with no significant difference between the two treatments.
Efficacy of triphala mouth rinse (aqueous extracts) on dental plaque and gingivitis in children.
RCT evaluating the efficacy of triphala mouth rinse in reducing plaque and gingivitis among 60 school children. Both triphala and chlorhexidine groups showed significant reductions in plaque and gingivitis, with no significant difference in gingival index change between groups. Chlorhexidine showed a higher percentage change in plaque index. Triphala is a cost-effective alternative for short-term use.
Antibacterial efficacy of triphala against oral streptococci: an in vivo study.
RCT investigating the effect of 6% triphala mouthwash on salivary streptococci levels compared to 0.2% chlorhexidine and plain water. The triphala group showed a 17% and 44% reduction in CFUs/ml at 48 hours and 7 days, respectively, closely paralleling the chlorhexidine group.
Assessment of antibacterial efficacy of triphala against mutans streptococci: a randomised control trial.
A double-blind randomized control trial assessed the antibacterial efficacy of triphala against salivary mutans streptococci in 57 high caries risk volunteers. Triphala mouthwash showed an 83% reduction in MS colony count at 15 days and a 67% reduction at 45 days, comparable to chlorhexidine, but without its side effects.
Study of the safety of oral Triphala aqueous extract on healthy volunteers.
An open-label, single-arm trial evaluated the safety of administering 2500 mg/day of aqueous Triphala extract to 20 healthy volunteers over four weeks. The study found no serious adverse effects and reported significant improvements in HDL-C levels and reductions in blood sugar levels.
Comparison of Antimicrobial Efficacy of Diode Laser, Triphala, and Sodium Hypochlorite in Primary Root Canals: A Randomized Controlled Trial
RCT comparing the antimicrobial efficacy of diode laser, triphala, and sodium hypochlorite against Enterococcus faecalis in primary root canals. The laser showed the most significant reduction in bacterial colony count, while triphala demonstrated better antibacterial activity than sodium hypochlorite, though not statistically significant.
Comparing the effect of different mouthrinses on de novo plaque formation.
RCT comparing the effect of Triphala, Hi Ora, Chlorhexidine, and Colgate Plax mouthwashes on de novo plaque formation in 30 subjects. Triphala and Hi Ora showed anti-plaque efficacy similar to Chlorhexidine and were more effective than Colgate Plax.
Efficacy of Smear Layer Removal of Human Teeth Root Canals Using Herbal and Chemical Irrigants: An In Vitro Study
In vitro study evaluating the smear layer removal efficacy of endodontic irrigants including 3% NaOCl, 17% EDTA, green tea extract, and Triphala extract on human teeth root canals. The study found that 17% EDTA had the highest smear layer removal efficacy, with Triphala also showing significant efficacy compared to distilled water.
A Systematic Review of Triphala Churna: A Focus on Ingredient Synergism and its Implications for Human Health
This narrative review explores the traditional uses and modern scientific evidence supporting the therapeutic potential of Triphala Churna and its constituent fruits. It highlights the synergistic interactions among the ingredients, contributing to improved digestion, enhanced immunity, antioxidant protection, and support for various chronic diseases.