Research

Thyme (Thymus vulgaris)

9 peer-reviewed studies curated from PubMed and Semantic Scholar.

0
Meta-analyses
1
Systematic reviews
7
RCTs
1
Other studies
Systematic reviews (11%)
RCTs (78%)

Studies

Sorted by quality and recency

2023·International journal of dental hygiene·Dicle Altındal, Kübra Ceran Deveci, Ayşe Gül Öner Talmaç, et al

Effects of thyme on halitosis in gingivitis patients: Can thyme mouthwash prevent halitosis-A randomized trial.

RCTn = 60

RCT evaluating the effect of thyme mouthwash on intraoral halitosis, gingival index, and plaque index in 60 gingivitis patients. Thyme mouthwash improved bad breath and gingivitis compared to control and other treatments.

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2007·Arzneimittel-Forschung·Bernd Kemmerich

Evaluation of efficacy and tolerability of a fixed combination of dry extracts of thyme herb and primrose root in adults suffering from acute bronchitis with productive cough. A prospective, double-blind, placebo-controlled multicentre clinical trial.

RCTn = 361

A double-blind, placebo-controlled RCT assessed the efficacy and tolerability of a thyme-primrose combination in 361 patients with acute bronchitis. The thyme-primrose group showed a 67.1% reduction in coughing fits compared to 51.3% in the placebo group, with faster symptom regression and higher responder rates. The treatment was well tolerated with no significant difference in adverse events between groups.

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2006·Arzneimittel-Forschung·Bernd Kemmerich, Reinhild Eberhardt, Holger Stammer

Efficacy and tolerability of a fluid extract combination of thyme herb and ivy leaves and matched placebo in adults suffering from acute bronchitis with productive cough. A prospective, double-blind, placebo-controlled clinical trial.

RCTn = 361

A double-blind, placebo-controlled clinical trial assessed the efficacy and tolerability of a thyme-ivy combination syrup in 361 patients with acute bronchitis. The thyme-ivy group showed a 68.7% reduction in coughing fits compared to 47.6% in the placebo group, with faster symptom regression and higher responder rates. The treatment was well tolerated with no significant difference in adverse events between groups.

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2004·Journal of herbal pharmacotherapy·Ethan Basch, Catherine Ulbricht, Paul Hammerness, et al

Thyme (Thymus vulgaris L.), thymol.

Systematic review

Systematic review of thyme (Thymus vulgaris L.) and thymol, covering scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

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2021·Journal of voice : official journal of the Voice Foundation·Sarah Frechen, Ewa V Latoszek

Effectiveness of Thymepearls After Vocal Loading in Professional Voice Users: A Randomized Placebo-Controlled Double-Blind Clinical Trial.

RCTn = 18

A randomized placebo-controlled double-blind clinical trial with 18 professional voice users assessed the effects of thymepearls after vocal loading. While no significant differences were observed in objective vocal measures, subjective improvements in dry mouth and hoarseness were noted in the thyme group compared to placebo.

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2006·Arzneimittel-Forschung·Joerg Gruenwald, Hans-Joachim Graubaum, Regina Busch

Evaluation of the non-inferiority of a fixed combination of thyme fluid- and primrose root extract in comparison to a fixed combination of thyme fluid extract and primrose root tincture in patients with acute bronchitis. A single-blind, randomized, bi-centric clinical trial.

RCTn = 189

A single-blind, randomized, bi-centric clinical trial evaluated the non-inferiority of a fixed combination of thyme fluid extract and primrose root extract compared to a combination of thyme fluid extract and primrose root tincture in 189 patients with acute bronchitis. Both combinations showed significant decreases in bronchitis symptoms with no significant difference between them, confirming the non-inferiority of the fluid extract combination.

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2005·Arzneimittel-Forschung·Joerg Gruenwald, Hans-Joachim Graubaum, Regina Busch

Efficacy and tolerability of a fixed combination of thyme and primrose root in patients with acute bronchitis. A double-blind, randomized, placebo-controlled clinical trial.

RCTn = 150Immunity

Double-blind, randomized, placebo-controlled trial of 150 patients with acute bronchitis comparing a fixed combination of thyme fluid extract and primrose root tincture to placebo. The verum group showed a significant decrease in Bronchitis Severity Score and a higher percentage of symptom-free patients compared to placebo, with good tolerability.

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2015·Drug research·S Ludwig, H Stier, S Weykam

Evaluation of Blood Alcohol Concentrations after Oral Administration of a Fixed Combination of Thyme Herb and Primrose Root Fluid Extract to Children with Acute Bronchitis.

RCTn = 16Inflammation

RCT evaluating the safety and efficacy of a fixed combination of thyme herb and primrose root fluid extract in children with acute bronchitis. Blood ethanol concentrations remained below safety thresholds, and the Bronchitis Severity Score significantly decreased, indicating positive effects on bronchitis symptoms.

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2005·Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine·Samuel Büechi, Roger Vögelin, Mónica Mennet von Eiff, et al

Open trial to assess aspects of safety and efficacy of a combined herbal cough syrup with ivy and thyme.

Studyn = 62

Open clinical trial assessing safety and efficacy of a combined herbal cough syrup containing ivy, thyme, aniseed, and marshmallow root in 62 patients with cough due to common cold, bronchitis, or respiratory tract diseases. Symptom scores improved, and efficacy and tolerability were rated as good or very good by most doctors and patients.

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