Research
Streptococcus Thermophilus
22 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Large-scale genome-wide analysis links lactic acid bacteria from food with the gut microbiome.
Large-scale genome-wide analysis of 9445 human metagenomes shows low prevalence and abundance of lactic acid bacteria (LAB) in stool samples, linked to age, lifestyle, and geography. Streptococcus thermophilus and Lactococcus lactis are most prevalent, suggesting fermented foods as a source of LAB for the gut microbiome.
Impact of synbiotics on disease activity in systemic lupus erythematosus: Results from a randomized clinical trial.
This randomized, double-blind, placebo-controlled clinical trial assessed the impact of synbiotics on IL-17A levels and disease activity in 50 SLE patients. The synbiotics group showed significant reductions in IL-17A levels and disease activity scores compared to baseline, suggesting potential as an adjunctive treatment for SLE.
The potential of Streptococcus thermophiles (TCI633) in the anti-aging.
RCT assessing the effects of Streptococcus thermophilus (TCI633) supplementation on skin health and aging. The study found that TCI633 promotes skin cell proliferation, increases collagen content, protects against DNA damage, and inhibits hyaluronidase activities, suggesting potential benefits for delaying skin aging.
The effect of a probiotic milk product on plasma cholesterol: a meta-analysis of short-term intervention studies.
Meta-analysis of six short-term intervention studies evaluating the effect of the probiotic milk product Gaio(R), containing Causido(R), on plasma cholesterol levels. The product showed a 4% decrease in total cholesterol and a 5% decrease in LDL-cholesterol compared to control groups.
The Ability of Streptococcus thermophilus BT01 to Modulate Urease Activity in Healthy Subjects' Fecal Samples Depends on the Biomass Production Process.
RCT evaluating the effect of manufacturing conditions on Streptococcus thermophilus BT01's ability to modulate urease activity in fecal samples of 20 healthy adults. The study found that S. thermophilus BT01 produced with Cryo-A decreased urease activity compared to Cryo-B.
Treatment efficacy of a probiotic preparation for non-alcoholic steatohepatitis: A pilot trial.
Open-label trial of 75 NASH patients comparing a probiotic cocktail to a control group over 12 weeks. The probiotic group showed significant reductions in serum ALT and liver stiffness, indicating reduced inflammation, and improved BMI and cholesterol levels compared to controls.
Streptococcus thermophilus fermented milk reduces serum MDA-LDL and blood pressure in healthy and mildly hypercholesterolaemic adults.
RCT of 59 adults comparing Streptococcus thermophilus-fermented milk to placebo for 12 weeks. The ST group showed significant reductions in MDA-LDL, MDA-LDL/LDL-cholesterol, and blood pressure, suggesting benefits for cardiovascular health and oxidative stress, especially in those with higher baseline oxidative stress.
Randomized, double-blind, placebo-controlled study of synbiotic yogurt effect on the health of children.
RCT assessing the effects of synbiotic yogurt on health, growth, and quality of life in children aged 12-48 months. Synbiotic yogurt reduced days of fever and improved social and school functioning, but increased frequency of bowel movements.
Randomised clinical trial: the synbiotic food supplement Probiotical vs. placebo for acute gastroenteritis in children.
RCT of 111 children with acute diarrhoea comparing the synbiotic food supplement Probiotical to placebo. The Probiotical group had a median diarrhoea duration of 3 days compared to 4 days in the placebo group, with higher rates of normal stool consistency and less additional medication use.
Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome.
This 8-week randomized, double-blind, placebo-controlled study assessed the effects of functional yogurt NY-YP901 on metabolic syndrome in 101 healthy participants. The treatment group showed significant reductions in body weight, BMI, and LDL-cholesterol compared to the control group.
Influence of synbiotic containing Lactobacillus acidophilus La5, Bifidobacterium lactis Bb 12, Streptococcus thermophilus, Lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial.
RCT of 90 critically ill patients in ICU comparing synbiotic preparation to placebo. Synbiotic group showed a significantly lower incidence of potentially pathogenic bacteria in nasogastric aspirates but no significant differences in intestinal permeability, septic complications, or mortality.
Effect of bifidobacterium Bb12 with or without Streptococcus thermophilus supplemented formula on nutritional status.
A double-blind, placebo-controlled trial in 148 children aged 6-36 months evaluated the effects of infant formula supplemented with Bifidobacterium Bb12 and Streptococcus thermophilus on nutritional status. The Bb12+ST group showed the highest increase in weight Z-score over 6 months, indicating better growth compared to the Bb12 and control groups.
Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases.
An 8-week RCT investigated the effect of probiotic milk products on cardiovascular risk factors in overweight and obese subjects. The CAUSIDO(R) culture reduced LDL-cholesterol and increased fibrinogen, with significant differences compared to placebo groups.
Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial.
RCT investigating the effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5, Bifidobacterium animalis ssp. lactis BB-12, and dietary fiber on the fecal microbiota of 30 adults with IBS. The synbiotic group showed a temporary increase in specific probiotic DNA in feces, but no significant changes in overall microbiota composition compared to placebo.
A combination of acid lactase from Aspergillus oryzae and yogurt bacteria improves lactose digestion in lactose maldigesters synergistically: A randomized, controlled, double-blind cross-over trial.
A randomized, controlled, double-blind cross-over trial on 24 lactose malabsorbers tested the effects of acid lactase from Aspergillus oryzae and yogurt bacteria on lactose digestion. The combination of acid lactase and yogurt cultures significantly improved lactose digestion and reduced symptoms of lactose intolerance compared to placebo.
Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults.
RCT of a synbiotic supplement containing various probiotics and fructooligosaccharides in 36 healthy adults. The synbiotic group showed significant improvement in self-reported gastrointestinal symptoms and bowel habits. A marginal effect on L-selectin was observed, suggesting a potential impact on immunoinflammatory status.
Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial.
Double blind randomized clinical trial of 28 NAFLD patients comparing a probiotic mixture of Lactobacillus bulgaricus and Streptococcus thermophilus to placebo for 3 months. The probiotic group showed decreased liver aminotransferase levels, while the placebo group showed no change.
Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome.
RCT of 30 D-IBS patients comparing probiotic fermented milk containing lactic acid bacteria to a placebo. Probiotic treatment significantly decreased small bowel permeability and improved global IBS scores, but did not affect colonic permeability.
Survival of yogurt bacteria in the human gut.
Study tested the survival of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus in the human gut by feeding 20 healthy volunteers commercial yogurt. Yogurt bacteria were found in human feces, suggesting they can survive transit in the gastrointestinal tract.
Effect of the lactic acid bacterium Streptococcus thermophilus on stratum corneum ceramide levels and signs and symptoms of atopic dermatitis patients.
RCT investigating the effects of a cream containing sonicated Streptococcus thermophilus on ceramide levels in the stratum corneum of atopic dermatitis patients. A 2-week application led to a significant increase in skin ceramide levels and improvement in AD symptoms such as erythema, scaling, and pruritus.
Effect of the lactic acid bacterium Streptococcus thermophilus on ceramide levels in human keratinocytes in vitro and stratum corneum in vivo.
The study investigated the effects of Streptococcus thermophilus on ceramide levels in vitro on cultured human keratinocytes and in vivo on the stratum corneum. In vitro, it enhanced ceramide levels in keratinocytes. In vivo, a cream containing sonicated Streptococcus thermophilus increased skin ceramide levels in 17 volunteers, potentially improving the lipid barrier and resistance against xerosis.
Impact of dietary yogurt on immune function.
RCT comparing the effects of 16 oz of yogurt containing live Lactobacillus bulgaricus and Streptococcus thermophilus versus 16 oz of milk on immune function in 20 adults with atopic histories. No significant improvements in immune parameters were noted.