Research
Stinging Nettle Root
12 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Neuroprotective effects of Urtica dioica Linn. on diabetic animal models: A systematic review.
Systematic review of preclinical studies on the neuroprotective effects of Urtica dioica in diabetic animal models. U. dioica demonstrated beneficial effects in mitigating diabetes-induced neural dysfunction through mechanisms like reducing oxidative stress and neuroinflammation, modulating insulin signaling, and promoting neurogenesis.
A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum)
A placebo-controlled, pseudo-randomized, crossover trial tested reishi mushroom, stinging nettle, and epimedium in 29 men with Gulf War Illness (GWI). Stinging nettle at higher doses significantly decreased GWI symptoms, while reishi increased symptom severity at higher doses. Epimedium showed no significant effect.
Effect of a galactagogue herbal tea on breast milk production and prolactin secretion by mothers of preterm babies.
RCT evaluating the effect of a galactagogue herbal tea containing stinging nettle on breast milk production and serum prolactin levels in mothers of preterm babies. The herbal tea increased milk production significantly compared to placebo and control groups, but there was no significant difference in serum prolactin levels or weight gain of babies.
Influence of the harvesting seasons on the polyphenol composition and antimicrobial activity of stinging nettle (Urtica dioica L.) extracts
The study investigated the polyphenol composition and antimicrobial activity of stinging nettle (Urtica dioica L.) extracts harvested in different seasons. Spring leaf extracts had higher polyphenol content and showed remarkable antimicrobial activity, particularly against Escherichia coli, Staphylococcus aureus, and Candida glabrata. Root extracts were less effective, though they inhibited Enterococcus faecalis.
Efficacy of Supportive Therapy of Allergic Rhinitis by Stinging Nettle (Urtica dioica) root extract: a Randomized, Double-Blind, Placebo- Controlled, Clinical Trial
RCT of 74 patients with allergic rhinitis comparing Urtica dioica (stinging nettle) to placebo for one month. Significant improvement in clinical symptom severity was observed in both groups, with a reduction in nasal smear eosinophil count in the nettle group. No significant changes in IgE, IL4, and IL5 levels, but a significant difference in IFN γ levels between groups.
Stinging nettle cream for osteoarthritis.
The paper likely studies the effects of stinging nettle cream on osteoarthritis, potentially focusing on joint and bone health.
Randomized controlled trial of nettle sting for treatment of base-of-thumb pain.
Randomized controlled double-blind crossover study in 27 patients with osteoarthritic pain at the base of the thumb or index finger. Patients applied stinging nettle leaf daily for one week, showing significantly greater reductions in pain and disability scores compared to placebo.
Gluten-Free Corn Cookies Incorporated With Stinging Nettle Leaf Flour: Effect on Physical Properties, Storage Stability, and Health Benefits
The study investigated the effect of incorporating stinging nettle leaf flour into gluten-free corn cookies on their nutritional and physical properties. Incorporation increased ash and protein content, total phenolic content, antioxidant activity, and decreased the estimated glycaemic index. Shelf life characteristics were within acceptable limits for 6 months.
Nettle Tea Inhibits Growth of Acute Myeloid Leukemia Cells In Vitro by Promoting Apoptosis
In vitro study investigating the anticancer properties of nettle tea on acute myeloid leukemia cell lines. Nettle tea inhibited proliferation and promoted apoptosis in AML cell lines, with alterations in Bax and Bcl-2 expression. The pro-apoptotic effects may be attributed to flavonoids and phenolics in the extract.
Screening of pharmacological uses of Urtica dioica and others benefits.
This narrative review discusses the pharmacological effects and various uses of Urtica dioica (stinging nettle). It highlights its historical use in cardiovascular disorders, glucose homeostasis, prostatic hyperplasia, rheumatoid arthritis, and as an adjunct in breast cancer treatment.
[Stinging nettle (Urtica dioica L.)--botanical characteristics, biochemical composition and health benefits].
The paper reviews the botanical characteristics, biochemical composition, and health benefits of stinging nettle (Urtica dioica L.). It highlights its antioxidant, antiplatelet, hypoglycaemic, and hypocholesterolemic properties, and discusses its potential use in chemoprevention, diabetes, benign prostatic hyperplasia, and urologic diseases.
Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy.
Exploratory study interviewing 18 self-selected patients using nettle sting of Urtica dioica for joint pain. Most patients reported significant benefits with no major side effects, suggesting nettle sting as a potentially useful therapy.