Research
Pea Protein
20 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Efficacy of Pea Protein Supplementation in Combination with a Resistance Training Program on Muscle Performance in a Sedentary Adult Population: A Randomized, Comparator-Controlled, Parallel Clinical Trial.
RCT comparing pea protein (PPr) to whey protein (WPr) in combination with resistance training in sedentary adults over 84 days. PPr supplementation resulted in a 16.1% improvement in whole-body muscle strength, comparable to WPr. Both supplements were safe and well-tolerated.
Efficacy and Safety of Pea Protein and Xyloglucan Versus Simethicone in Functional Abdominal Bloating and Distension.
This double-blind, multicenter, randomized study evaluated the safety and efficacy of a product containing xyloglucan and pea proteins compared with simethicone in 88 patients with Functional Abdominal Bloating and Distension (FABD). The XG+PP group showed a faster onset of action and significant reduction in bloating, abdominal pain, and abdominal girth compared to simethicone, along with a significant reduction in hydrogen breath test results.
A randomized controlled trial in healthy participants to compare the insulinogenic effects of whey protein and pea protein co-ingested with glucose.
This single-blind, randomized, crossover study compared the effects of co-ingesting glucose with 10 or 20 g whey protein and glucose with 10 or 20 g pea protein on glycaemic and insulinaemic responses in 30 healthy individuals. The study found that glucose with 20 g pea protein significantly reduced the glycaemic response compared to glucose alone, and had a lower insulinaemic response compared to glucose with 20 g whey protein.
Randomized Controlled Trial: Effects of a Bitter-Tasting Pea Protein Hydrolysate Intervention With Low Degree of Hydrolyzation on Energy Intake in Moderately Overweight Male Subjects.
This randomized controlled trial studied the effects of pea protein hydrolysates (PPHs) with varying bitterness and degrees of hydrolysis on satiety in 19 moderately overweight men. PPH2 (more bitter, lower DH) reduced energy intake and delayed gastric emptying, while PPH1 (less bitter, higher DH) decreased plasma ghrelin and DPP-4 levels, promoting satiety.
Recovery of Strength After Exercise-Induced Muscle Damage in Vegetarians Consuming the Upper and Lower Ends of Protein Recommendations for Athletes.
Crossover RCT assessing recovery of strength, power, and soreness after exercise-induced muscle damage in vegetarians consuming different levels of protein, supplemented with pea protein. No difference in recovery was found between the lower and upper protein intake groups.
Plant Protein Blend Ingestion Stimulates Postexercise Myofibrillar Protein Synthesis Rates Equivalently to Whey in Resistance-Trained Adults.
RCT comparing postexercise myofibrillar protein synthesis rates in resistance-trained adults after ingesting a plant protein blend versus whey protein. The plant protein blend stimulated MyoPS to an equivalent extent as whey protein, suggesting its utility for optimizing postexercise skeletal muscle reconditioning.
Postprandial plasma aminoacidemia and indices of appetite regulation following pea-rice blend, pea isolate and whey protein ingestion in healthy young adults.
This study assessed plasma amino acids and appetite hormones following ingestion of a pea-rice protein blend, pea-only, and whey protein in a randomised, double-blind, crossover design with ten healthy adults. The mean plasma essential amino acid incremental AUC was higher in whey compared to pea and blend, with no differences between pea and blend. No differences in appetite or energy intake responses were observed between treatments.
High-Moisture Extrusion of a Dietary Protein Blend Impairs In Vitro Digestion and Delays In Vivo Postprandial Plasma Amino Acid Availability in Humans.
RCT with 9 healthy volunteers comparing a 'dry' blend of mycoprotein/pea protein to a high-moisture extruded (HME) blend. The HME process impaired in vitro digestion and delayed in vivo postprandial plasma amino acid availability, likely due to impaired gastric phase digestion.
The Muscle Protein Synthetic Response to the Ingestion of a Plant-Derived Protein Blend Does Not Differ from an Equivalent Amount of Milk Protein in Healthy Young Males.
RCT comparing postprandial muscle protein synthesis rates following ingestion of 30g milk protein versus a 30g plant-derived protein blend (wheat, corn, pea) in 24 healthy young males. Both protein sources increased muscle protein synthesis rates with no significant differences between them.
Values for the Digestibility of Pea Protein Isolate or Casein Amino Acids Determined using the Dual Isotope Method Are Not Similar to Those Derived with the Standard Ileal Balance Method in Healthy Volunteers.
The study compared the indispensable amino acid digestibility values of pea protein and casein using the dual isotope and standard ileal balance methods in 15 healthy adults. For pea protein, mean digestibility was similar between methods, but individual amino acid values varied. For casein, digestibility was lower with the dual isotope method.
Real ileal amino acid digestibility of pea protein compared to casein in healthy humans: a randomized trial.
This randomized trial compared the real ileal amino acid and nitrogen digestibility of pea protein isolate to milk casein in 15 healthy volunteers. The study found no significant difference in digestibility or net postprandial protein utilization between the two proteins, with pea protein demonstrating a DIAAS of 1.00, indicating its potential as a high-quality protein source.
Efficacy and safety of Gelsectan for diarrhoea-predominant irritable bowel syndrome: A randomised, crossover clinical trial.
This double-blind, crossover RCT evaluated the efficacy and safety of a combination of xyloglucan, pea protein, tannins from grape seed extract, and xylo-oligosaccharides in 60 patients with diarrhoea-predominant IBS. The treatment significantly improved stool consistency and alleviated symptoms like abdominal pain and bloating compared to placebo, with no adverse events reported.
Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein
This double-blind, randomized, placebo-controlled clinical trial compared the effects of pea protein, whey protein, and placebo on biceps brachii muscle thickness and strength during a 12-week resistance training program in 161 males. Pea protein supplementation resulted in greater muscle thickness gains compared to placebo, particularly in weaker participants, while no significant difference was found between pea and whey protein groups.
Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals.
RCT evaluating the effects of lupin protein and pea protein/fibre combinations on cholesterol levels in moderately hypercholesterolaemic individuals. Significant reductions in total cholesterol were observed with lupin protein+cellulose, casein+apple pectin, pea protein+oat fibre, and pea protein+apple pectin combinations.
Long-term safety and efficacy study of a medical device containing xyloglucan, pea protein reticulated with tannins and xylo-oligosaccharides, in patients with diarrhoea-predominant irritable bowel syndrome
This observational study evaluated the long-term safety and efficacy of a medical device containing xyloglucan, pea protein, tannins, and xylo-oligosaccharides in 50 adult patients with diarrhoea-predominant irritable bowel syndrome (IBS-D). The treatment improved IBS-D symptoms, including IBS Symptom Severity Score, diarrhoea, pain, and bloating, with mild adverse effects mostly unrelated to the treatment.
Rate of appearance of amino acids after a meal regulates insulin and glucagon secretion in patients with type 2 diabetes: a randomized clinical trial.
RCT comparing the effects of isolated pea protein-based (PP) and casein protein-based (CP) meals on endocrine responses in 37 patients with type 2 diabetes. CP meals resulted in lower insulin and glucagon release compared to PP meals, with improved insulin sensitivity and secretion after CP intake. The study suggests that protein quality impacts glucose metabolism and insulin needs.
Acute effects of pea protein and hull fibre alone and combined on blood glucose, appetite, and food intake in healthy young men--a randomized crossover trial.
Randomized crossover trial with 15 healthy young men examining the effects of pea protein, pea hull fibre, and their combination on blood glucose, appetite, and food intake. Pea protein plus fibre and yellow peas led to lower blood glucose levels compared to fibre and control, supporting their use in foods for glycemic control.
The effect of yellow pea protein and fibre on short-term food intake, subjective appetite and glycaemic response in healthy young men.
RCT investigating the effects of 10 or 20 g of isolated yellow pea protein or fibre on food intake, blood glucose, and appetite in healthy young males. P20 led to lower food intake and suppressed blood glucose compared to control, but had no effect on appetite. The effects were not observed 2 hours post-consumption.
Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese male subjects.
RCT investigating the effects of intraduodenal administration of pea protein on food intake in lean and obese male subjects. The study found that bypassing gastric digestion increased satiety hormone levels and reduced food intake, particularly in obese subjects, compared to oral administration.
A New Approach for the Treatment of Recurrent Vulvovaginal Candidiasis with a Combination of Pea Protein, Grape Seed Extract, and Lactic Acid Assessed In Vivo
An animal study using a murine model of Candida albicans-induced recurrent vulvovaginal candidiasis (RVVC) evaluated the efficacy of a topical product containing pea protein, grape seed extract, and lactic acid. The combination significantly preserved vaginal tissue architecture, prevented vaginal inflammation, and increased azole efficacy, demonstrating its potential for managing RVVC.