Research
Nettle
9 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: A systematic review and meta‐analysis
Systematic review and meta-analysis of 8 RCTs with 401 participants assessing the effect of nettle supplementation on glycemic markers in T2DM patients. Nettle supplementation significantly reduced fasting blood sugar concentrations but showed no significant effect on insulin levels, insulin resistance index, or glycosylated hemoglobin percentage.
Comparison of the Effect of Cumin Cyminum and Nettle Oral Drops on the Breast Milk Sufficiency Indicators in New Mothers.
Triple-blind RCT comparing the effects of cumin and nettle oral drops on breast milk adequacy indicators in 117 lactating mothers. Both cumin and nettle increased milk production indicators compared to placebo, with cumin showing greater effectiveness.
The effect of nettle vaginal cream on subjective symptoms of vaginal atrophy in postmenopausal women.
This triple-blind randomized placebo-controlled clinical trial studied the effect of 5% nettle vaginal cream on subjective symptoms of vaginal atrophy in 84 postmenopausal women. The study found that nettle cream significantly reduced symptoms such as vaginal burning, dryness, itching, and dyspareunia compared to placebo.
The effect of Urtica Dioica leaf extract intake on serum TNF-α, stool calprotectin and erythrocyte sedimentation rate in patients with inflammatory bowel disease: A double-blind, placebo-controlled, randomized, clinical trial
Double-blind, placebo-controlled RCT on 64 IBD patients assessing Urtica Dioica leaf extract's effect on inflammation markers. The Urtica Dioica group showed significant reductions in TNF-α and fecal calprotectin levels compared to placebo, indicating improved inflammatory status.
A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri Combination Significantly Reduces Gonarthritis Symptoms in a Randomized, Placebo-Controlled Double-Blind Study.
This 12-week randomized, placebo-controlled double-blind study investigated the efficacy and safety of MA212, a combination of rosehip, nettle, devil's claw, and vitamin D, in patients with gonarthritis. The MA212 group showed significant improvement in WOMAC pain scores and quality of life compared to placebo, with a trend towards reduced analgesic consumption.
Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial.
RCT evaluating the effects of nettle leaf extract on glycemic control in 92 patients with advanced type 2 diabetes mellitus needing insulin. Nettle extract significantly lowered fasting glucose, postprandial glucose, and HbA1c levels compared to placebo, without significant effects on other parameters.
The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial.
RCT evaluating the effects of hydro alcoholic nettle extract on oxidative stress in 50 patients with type 2 diabetes over 8 weeks. The intervention group showed significant increases in Total Antioxidant Capacity (TAC) and Superoxidant Dismutase (SOD) compared to the control group.
The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
RCT of hydro alcoholic extract of nettle on insulin sensitivity and inflammatory indicators in 50 type 2 diabetic patients over 8 weeks. The intervention group showed significant decreases in IL-6 and hs-CRP compared to the control group.
Silk fibroin and Nettle extract promote wound healing in a rat model: A histological and morphometrical study.
The study investigated the effects of Nettle leaf extract and silk fibroin on wound healing in a rat model. Results showed that both substances promoted wound closure, reduced cell apoptosis, and enhanced cell proliferation, contributing to improved skin health and wound remodeling.