Research
Magnesium Glycinate
9 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial.
This randomized, double-blind, placebo-controlled trial assessed the effects of magnesium bisglycinate supplementation on insomnia symptoms in 155 adults with poor sleep quality. The magnesium group showed a significantly greater reduction in Insomnia Severity Index scores compared to placebo, indicating a modest benefit.
Association between Serum Magnesium Level and Depression in Selective Serotonin Reuptake Inhibitors Treated Major Depressive Disorder Patients
A randomized, double-blind, placebo-controlled trial in Bangladesh studied the effect of magnesium glycinate supplementation on depression in patients with major depressive disorder treated with SSRIs. The study found that increased serum magnesium levels were associated with decreased depression scores over 8 weeks.
Research on Synergistic Regulation of Sleep-Emotion-Behavior Based on SLS Magnesium Glycinate Complex Liquid Supplement
A 3-month clinical trial of SLS Magnesium Glycinate Complex Liquid Supplement in children and adolescents with ADHD showed improvements in sleep efficiency by 15%-23%, reduced tic frequency by 21%-32%, and enhanced emotional stability scores by 24%-30%. The formula is designed for age-specific developmental needs and demonstrated good safety and tolerability.
The effect of combined magnesium and vitamin D supplementation on vitamin D status, systemic inflammation, and blood pressure: A randomized double-blinded controlled trial.
This 12-week double-blinded randomized controlled trial compared the effects of combined magnesium and vitamin D supplementation versus vitamin D alone on serum 25-hydroxyvitamin D concentrations, blood pressure, and inflammation in 95 overweight and obese participants. The combined supplementation group showed a greater increase in serum 25OHD and a decrease in systolic blood pressure for those with high baseline levels, but no significant effects on inflammation markers.
Abstract P161: Randomized Trial Of Magnesium Glycinate Supplementation And Blood Pressure In Middle-aged Adults
Randomized, double-blind, placebo-controlled trial testing 480 mg/d of elemental magnesium glycinate versus placebo for 12 weeks in 59 participants with elevated seated blood pressure. The study found no significant effect of magnesium glycinate on seated or 24-hour blood pressure compared to placebo.
Study of Magnesium Formulations on Intestinal Cells to Influence Myometrium Cell Relaxation
In vitro study comparing the effects of magnesium bisglycinate and sucrosomial magnesium on intestinal cell permeability and myometrial cell relaxation. Magnesium bisglycinate showed better intestinal absorption and myometrial relaxation, indicating potential effectiveness in human applications.
Effect of chronic administration of magnesium supplement (magnesium glycinate) on male albino wistar rats’ intestinal (Ileum) motility, body weight changes, food and water intake
Animal study on the effects of chronic administration of magnesium glycinate on intestinal motility in male albino Wistar rats. Magnesium decreased motility of the intestine through the beta adrenergic receptor pathway, with significant differences in ileum contractions compared to the control group.
A Challenging Case of Hypercalcemia Caused by a Novel Homozygous Variant Missense Mutation in theGene.
Case report of a 26-year-old male with persistent hypercalcemia due to a novel homozygous missense pathogenic variant affecting vitamin D metabolism. The patient was treated with fluconazole and magnesium glycinate, resulting in a reduction of calcium levels from 12.7 mg/dL to 9.4 mg/dL over 3 months.
Rapid Resolution of Chronic Back Pain with Magnesium Glycinate in a Pediatric Patient
Case report of a 10-year-old male with chronic back pain due to corticosteroid-induced osteoporosis. Treatment with oral magnesium glycinate and topical magnesium/guaifenesin cream resulted in rapid and sustained pain reduction, increased flexibility, and improved quality of life.