Research
Lemongrass
14 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Comparative Evaluation of 0.25% Lemongrass Oil Mouthwash and 0.2% Chlorhexidine Mouthwash in Fixed Orthodontic Patients Suffering from Gingivitis.
RCT comparing the antiplaque and antigingivitis efficacy of 0.25% lemongrass oil mouthwash to 0.2% chlorhexidine mouthwash in 60 orthodontic patients with gingivitis. Lemongrass oil mouthwash showed significantly lower plaque and gingival index scores by the 14th and 21st days, suggesting it as a potential herbal alternative.
Effect of aromatherapy with lemongrass (Cymbopogon citratus) on the anxiety of patients undergoing scaling and root planning: a randomized clinical trial.
RCT investigating the effects of lemongrass aromatherapy on anxiety and hemodynamic factors in patients undergoing nonsurgical periodontal treatment. Lemongrass aromatherapy significantly reduced systolic and diastolic blood pressure, heart rate, and anxiety scores.
Comparative Evaluation of Locally Administered 2% Gel Fabricated from Lemongrass Polymer and 10% Doxycycline Hyclate Gel as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis—A Randomized Controlled Trial
This double-blind parallel arm randomized controlled trial compared the antimicrobial effectiveness of 2% lemongrass gel and 10% doxycycline hyclate gel as adjuncts to scaling and root planing in treating chronic periodontitis. Both treatments significantly reduced clinical indices and microbial colony counts from baseline to 1st and 3rd month follow-ups.
Bioactive natural constituents from lemongrass tea and erythropoiesis boosting effects: potential use in prevention and treatment of anemia.
RCT assessing the effects of lemongrass tea on hematologic indices in 105 human volunteers. Lemongrass tea significantly increased PCV, Hb, and RBC, particularly in the subchronic phase, suggesting an erythropoiesis boosting effect.
Effect of lemongrass tea consumption on estimated glomerular filtration rate and creatinine clearance rate.
RCT investigating the effects of lemongrass tea on renal function indices in 105 subjects. Lemongrass tea consumption led to significant decreases in creatinine clearance rate and estimated glomerular filtration rate, with dose- and time-dependent adverse effects observed.
Treatment of oral thrush in HIV/AIDS patients with lemon juice and lemon grass (Cymbopogon citratus) and gentian violet.
RCT comparing lemon juice, lemon grass, and gentian violet for treating oral thrush in HIV/AIDS patients. Lemon juice showed better results than gentian violet, and lemon grass was also effective. The study validated the use of lemon juice and lemon grass for oral candidiasis in this population.
Periodontal Therapy with 0.25%Lemongrass Oil Mouthwash in Reducing Risk of Cardiovascular Diseases: A 3-Arm Prospective Parallel Experimental Study.
A double-blinded randomized clinical trial with 45 subjects with severe periodontitis compared 0.25% lemongrass oil mouthwash, 0.12% chlorhexidine mouthwash, and oral prophylaxis. The lemongrass oil group showed significant reductions in C-Reactive Protein, Probing Pocket Depth, Clinical Attachment Loss, Total Cholesterol, and Low Density Lipid levels, suggesting benefits for periodontal and cardiovascular health.
Anti-dandruff Hair Tonic Containing Lemongrass (Cymbopogon flexuosus) Oil.
A randomized, double-blind, placebo-controlled study with 30 Thai volunteers evaluated the efficacy of a hair tonic containing lemongrass oil against dandruff. The tonic with 5, 10, or 15% lemongrass oil significantly reduced dandruff at days 7 and 14, with the 10% formulation being the most effective.
Antimicrobial effect of lemongrass oil against oral malodour micro-organisms and the pilot study of safety and efficacy of lemongrass mouthrinse on oral malodour.
The study investigated the antimicrobial activity of lemongrass oil mouthrinse against odourigenic micro-organisms and its efficacy in reducing oral malodour in 20 healthy volunteers. The lemongrass oil mouthrinse was effective against certain bacteria and significantly reduced volatile sulphur compounds, indicating a reduction in oral malodour.
Treatment of pityriasis versicolor with topical application of essential oil of Cymbopogon citratus (DC) Stapf - therapeutic pilot study.
Phase I and II clinical studies evaluated the safety and efficacy of essential oil of Cymbopogon citratus in treating pityriasis versicolor. Phase I confirmed safety, while Phase II showed a 60% mycological cure rate with essential oil treatment compared to over 80% with ketoconazole.
Pharmacology of lemongrass (Cymbopogon citratus Stapf). III. Assessment of eventual toxic, hypnotic and anxiolytic effects on humans.
RCT assessing the toxic, hypnotic, and anxiolytic effects of lemongrass tea in healthy volunteers. Lemongrass showed no significant changes in various biochemical parameters and no hypnotic or anxiolytic effects compared to placebo.
Antibacterial Efficacies of Extracts of Lemon Grass (Cymbopogon citratus) on Some Clinical Microbial Isolates
In vitro study investigating the antimicrobial activity of aqueous and ethanolic extracts of lemon grass (Cymbopogon citratus) against clinical isolates. The aqueous extract showed higher antimicrobial activity against all test isolates compared to the ethanolic extract, which was effective only against P. aeruginosa and S. aureus. Both extracts exerted a bacteriostatic effect.
Nutritional Aspects, Chemistry Profile, Extraction Techniques of Lemongrass Essential Oil and It's Physiological Benefits.
This narrative review covers the nutritional aspects, chemistry profile, and extraction techniques of lemongrass essential oil. It discusses the physiological benefits of lemongrass oil, including its impact on diabetic wound healing, tissue repair, arthritis, and joint pain. The review also highlights the effectiveness of different extraction methods and the oil's application in aromatherapy.
Lemongrass Extract Possesses Potent Anticancer Activity Against Human Colon Cancers, Inhibits Tumorigenesis, Enhances Efficacy of FOLFOX, and Reduces Its Adverse Effects
The study investigates the anticancer effects of lemongrass extract on human colorectal cancer models. Lemongrass extract induced apoptosis in colon cancer cells and inhibited tumor growth in mice. It enhanced the efficacy of FOLFOX chemotherapy and reduced its adverse effects, such as weight loss, in animal models.