Research

Diatomaceous Earth (Food Grade)

7 peer-reviewed studies curated from PubMed and Semantic Scholar.

0
Meta-analyses
0
Systematic reviews
2
RCTs
5
Other studies
RCTs (29%)
Observational (14%)

Studies

Sorted by quality and recency

2024·Journal of animal science·Aristide Maggiolino, Maria Federica Sgarro, Elisabetta Casalino, et al

Use of a commercial feed supplement based on diatom earth and yeast products on oxidative status and in vitro immune response in buffaloes during peripartum.

RCTn = 80Immunity

RCT evaluating the effect of a commercial feed additive based on diatomaceous earth and hydrolyzed yeasts on health status, milk quality, and immune response in 80 buffalo cows during the transition period. The additive enhanced total antioxidant capacity and enzyme activity, reduced ROS synthesis in polymorphonuclear cells, and supported a potential positive response in animals experiencing inflammation.

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2025·Food & function·M Pilar Vaquero, María Dolores Álvarez, Belén Zapatera, et al

Postprandial metabolism of a reduced-fat meat product with added silicon from diatomaceous earth. A pilot randomized controlled four-way assay in humans.

RCTn = 18

A four-way postprandial randomized crossover-controlled trial in 18 adults tested a reduced-fat meat product with added silicon from diatomaceous earth. Results showed that postprandial serum silicon and triglycerides increased, insulin increased during the first hour and decreased thereafter, while glucose remained unchanged. Silicon from diatomaceous earth was unabsorbed and had no effect on normal postprandial metabolism.

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2026·Foods (Basel, Switzerland)·Rocío Redondo-Castillejo, Claudia Quevedo-Torremocha, María Luisa de la Cruz Conty, et al

Antidiabetic Effect of Substituting Processed Meat with Reduced-Fat and Diatomaceous Earth-Enriched Pâtés in Middle-Aged Female Wistar Rats.

Animal studyNutrition

The study evaluates the antidiabetic effects of replacing commercial pâté with silicon-enriched and reduced-fat pâtés in middle-aged female Wistar rats. Silicon from diatomaceous earth incorporated into pâté improved health markers such as serum glucose, insulin, and cholesterol levels, suggesting its potential as a nutritional adjuvant for diabetes management.

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2025·Nutrients·Rocío Redondo-Castillejo, Marina Hernández-Martín, Jousef Ángel Issa-García, et al

Diatomaceous Earth Supplementation as a Bioavailable Silicon Source Modulates Postprandial Lipid Metabolism in Healthy Female Rats.

Animal studyNutrition

The study investigated the effects of diatomaceous earth (DE) supplementation as a silicon source on lipid metabolism in healthy female rats. DE enhanced silicon absorption, reduced postprandial triglyceridemia, and increased luminal triglyceride retention, indicating a reduction in intestinal lipid absorption and enhanced cholesterol efflux.

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2025·Gels (Basel, Switzerland)·María Dolores Álvarez, Arancha Saiz, Susana Cofrades

Novel Fat Replacers Based on Pork Lard and a Cold Gelling System in the Reformulation of Reduced-Fat Fresh Pork Sausages Containing Silicon from Diatomaceous Earth Powder.

In vitroNutrition

The study investigates the use of emulsion gel and fat bulking agent as animal fat replacers in reduced-fat pork sausages, with and without added silicon from diatomaceous earth powder. The reformulated sausages showed adequate physicochemical characteristics and reduced lipid digestibility, with silicon further limiting fat digestion.

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2025·Experimental & applied acarology·Liang Dong, Oriel Thekisoe, Tsepo Ramatla, et al

Acaricidal effects of diatomaceous earth on Haemaphysalis longicornis under laboratory conditions.

In vitro

The study evaluated the acaricidal effects of diatomaceous earth (DE) on different life stages of Haemaphysalis longicornis ticks under laboratory conditions. DE was found to cause 100% mortality in larvae, nymphs, and adult ticks within specific time frames, suggesting its potential as a safe alternative to chemical acaricides.

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1998·European journal of medical research·H Wachter, M Lechleitner, E Artner-Dworzak, et al

Diatomaceous earth lowers blood cholesterol concentrations.

Observationaln = 19Heart Health

Study of 19 healthy individuals with moderate hypercholesterinemia taking 250 mg diatomaceous earth three times daily for 8 weeks. Significant reductions in serum cholesterol, low-density lipoprotein cholesterol, and triglycerides were observed, with increases in high-density lipoprotein cholesterol after stopping intake.

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