Research
Codonopsis
7 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Codonopsis Radix: A comprehensive review for its ethnopharmacology, phytochemistry, pharmacodynamics, pharmacokinetics, toxicity and potential clinical applications.
This systematic review integrates information on the ethnopharmacology, phytochemistry, pharmacokinetics, toxicity, and pharmacodynamics of Codonopsis Radix. It highlights its effects on immunity, gut health, brain health, and inflammation, and discusses its absorption and metabolism.
Dang shen [Codonopsis pilosula (Franch.) Nannf] herbal formulae for chronic obstructive pulmonary disease: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of Dang shen (Codonopsis pilosula) formulae for treating chronic obstructive pulmonary disease (COPD). The analysis included 48 randomized controlled trials and found that Dang shen formulae improved lung function, quality of life, and exercise capacity compared to conventional pharmacotherapy and placebo. Adverse events were low and not significantly different between groups.
Beneficial effects of Codonopsis lanceolata extract on systolic blood pressure levels in prehypertensive adults: A double-blind, randomized controlled trial.
This randomized controlled trial investigated the effects of Codonopsis lanceolata extract on systolic blood pressure in prehypertensive adults. The study found that CL extract significantly decreased systolic BP and increased catalase activity. It also improved serum nitrite concentration, reduced high sensitivity C-reactive protein, and decreased malondialdehyde levels, indicating benefits in preventing endothelial dysfunction, inflammation, and lipid peroxidation.
Effects of a Chinese medical herbs complex on cellular immunity and toxicity-related conditions of breast cancer patients.
A randomized, double-blind, placebo-controlled study examined the effects of a Chinese medicinal herb complex (RG-CMH) on immune cell counts in 58 breast cancer patients undergoing chemotherapy or radiotherapy. RG-CMH administration was associated with a significant reduction in leucocyte and neutrophil levels compared to placebo, though differences in T cell levels were not statistically significant.
Dangshen (Codonopsis pilosula) and Bai guo (Gingko biloba) enhance learning and memory.
Double-blind randomized placebo-controlled trial testing Gingko biloba alone and in combination with Codonopsis pilosula on memory acquisition and retention in 60 participants. Both products improved cognitive function and overall health compared to placebo, with the combination product showing superior effects.
[Clinical study of medicinal-cake-separated moxibustion for senile osteoporosis].
RCT comparing medicinal-cake-separated moxibustion using a herbal mixture to wheat-flour-cake moxibustion in 60 patients with senile osteoporosis. The herbal moxibustion group showed significant improvements in symptom scores, lumbar and hip bone mineral density, and serum markers compared to the control group.
[Protective effects of new compound codonopsis tablets against acute mountain sickness].
RCT of 45 male soldiers studying the effects of new compound codonopsis tablets on acute mountain sickness (AMS). The treatment group showed reduced AMS symptoms and improved breathing function compared to control, indicating a protective effect against AMS.