Research
Burdock Root
9 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Beneficial effect of Burdock complex on asymptomatic Helicobacter pylori-infected subjects: A randomized, double-blind placebo-controlled clinical trial.
RCT of Burdock complex (BC) on asymptomatic H. pylori-infected subjects and AGS cell model. BC significantly decreased UBT values, inflammatory markers, and improved antioxidant activity and phenolic levels compared to placebo, suggesting anti-H. pylori activity.
Effects of aquarobic exercise and burdock intake on serum blood lipids and vascular elasticity in Korean elderly women.
RCT analyzing the effects of aquarobic exercise and burdock intake on serum blood lipids and vascular elasticity in elderly women over 12 weeks. The combination of aquarobic exercise and burdock intake significantly decreased total cholesterol, triglycerides, HDL-C, and LDL-C levels, suggesting improvements in heart health.
Effects of Arctium lappa L. (Burdock) root tea on inflammatory status and oxidative stress in patients with knee osteoarthritis.
RCT of 36 patients with knee osteoarthritis examining the effects of Burdock root tea on inflammatory markers and oxidative stress. Burdock root tea significantly decreased serum IL-6, hs-CRP, and malondialdehyde levels, while increasing serum TAC and SOD activities, suggesting improvements in inflammatory status and oxidative stress.
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.
The study investigates the effects of ethanolic extract of Arctium lappa L root (ALE) on obesity and hepatic steatosis in rats. ALE was found to regulate lipid metabolism, reduce triglyceride and cholesterol levels in the liver, and ameliorate hepatic steatosis by activating the AMPK/ACC/CPT-1 pathway, suggesting potential benefits for metabolic-associated fatty liver disease and obesity.
Effect of Dose and Timing of Burdock (Arctium lappa) Root Intake on Intestinal Microbiota of Mice
The study investigated the effects of burdock (Arctium lappa) root intake on the intestinal microbiota of mice fed a high-fat diet. It found that burdock root, which contains inulin and polyphenols, had a stronger effect on microbiota diversity than inulin alone, with evening intake showing a more pronounced effect.
Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications
Narrative review of Arctium lappa (burdock) highlighting its pharmacological properties and therapeutic applications. The root extract shows potential in addressing hepatotoxicity, oxidative stress, and exhibits antidiabetic, hypolipidemic, aphrodisiac, anti-rheumatic, and anti-Alzheimer properties.
Burdock (Arctium lappa L) roots as a source of inulin-type fructans and other bioactive compounds: Current knowledge and future perspectives for food and non-food applications.
This review highlights the potential of burdock roots as a source of prebiotic fibers and bioactive compounds like chlorogenic acids and quercetin. It discusses the antioxidant, anti-inflammatory, hypolipidemic properties, and gastric mucosal defense mechanisms of burdock roots, suggesting their use as functional food.
Burdock (Arctium lappa L.) root attenuates preneoplastic lesion development in a diet and thioacetamide‐induced model of steatohepatitis‐associated hepatocarcinogenesis
The study investigated the effects of burdock root ethanolic extract (BRE) on NASH-associated hepatocarcinogenesis in male Wistar rats. BRE administration reduced fatty acid and lipid hydroperoxide levels, increased antioxidant enzyme activities, and diminished the size of preneoplastic lesions, suggesting potential therapeutic effects in liver health.
Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root’s hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice
The study evaluated the antidiabetic and hypolipidemic properties of Arctium lappa root extract on nicotinamide-streptozotocin-induced type 2 diabetes in mice. The extract decreased triglyceride, very low density lipoprotein, glucose, and alkaline phosphatase levels, while increasing insulin, HDL, and leptin levels, suggesting its potential benefits in diabetes treatment.