Research
Arabinogalactan
10 peer-reviewed studies curated from PubMed and Semantic Scholar.
Studies
Sorted by quality and recency
Citrus tamurana Hort. ex Tanaka (Hyuganatsu orange)-derived arabinogalactan suppresses bone turnover in postmenopausal women: A randomized placebo-controlled study.
RCT evaluating arabinogalactan-rich Hyuganatsu juice on bone turnover in 63 postmenopausal women. The study group showed significantly lower TRACP5b and P1NP levels at day 90 compared to the control group, indicating suppressed bone mineral turnover.
A randomized double-blind controlled proof-of-concept study of alanyl-glutamine for reduction of post-myomectomy adhesions.
A randomized double-blind controlled study tested the effect of intraperitoneal alanyl-glutamine on reducing post-myomectomy adhesions in 38 women. The study found that alanyl-glutamine significantly reduced the incidence, severity, and extent of adhesions compared to placebo, with no serious adverse events reported.
Effect of arabinogalactan on the gut microbiome: A randomized, double-blind, placebo-controlled, crossover trial in healthy adults.
Randomized, double-blind, placebo-controlled, crossover trial in 30 healthy adults to investigate the effect of arabinogalactan (ResistAid) on the gut microbiome. ResistAid supplementation led to a significant decrease in the ratio of fecal Firmicutes to Bacteroidetes and increased Bifidobacterium abundance. It also increased gene abundance for certain gut microbiome functions and decreased specific fecal acids, with no significant changes in gastrointestinal tolerance, suggesting safety.
Larch arabinogalactan effects on reducing incidence of upper respiratory infections.
A placebo-controlled, double-blind RCT with 199 participants assessed the effect of larch arabinogalactan on common cold incidence. Arabinogalactan supplementation significantly reduced the number of participants affected by colds and tended to decrease cold incidence. The severity of symptoms at episode start was higher with arabinogalactan, but the treatment was well tolerated.
Randomised clinical trial: efficacy of a new synbiotic formulation containing Lactobacillus paracasei B21060 plus arabinogalactan and xilooligosaccharides in children with acute diarrhoea.
Double-blind, randomised, placebo-controlled trial testing a synbiotic formulation containing Lactobacillus paracasei B21060, arabinogalactan, and xilooligosaccharides in children with acute diarrhoea. The synbiotic group showed higher resolution rates of diarrhoea at 72 hours, reduced duration of diarrhoea, daily stool outputs, and stool consistency compared to placebo.
The association of a probiotic with a prebiotic (Flortec, Bracco) to improve the quality/quantity of spermatozoa in infertile patients with idiopathic oligoasthenoteratospermia: a pilot study.
Pilot RCT of 41 infertile patients with idiopathic oligoasthenoteratospermia comparing Flortec (a probiotic and prebiotic combination) to a control substance. Flortec improved sperm count, concentration, motility, and typical forms, as well as FSH, LH, and testosterone levels, with no side effects.
L-alanyl-L-glutamine ingestion maintains performance during a competitive basketball game
This study examined the effects of L-alanyl-L-glutamine ingestion on basketball performance in 10 NCAA Division I female basketball players. The AG supplement improved basketball shooting performance and visual reaction time compared to dehydration and water-only trials, and reduced fatigue compared to dehydration.
Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers.
This randomized, double-blind, placebo-controlled pilot study tested the effect of a proprietary arabinogalactan extract (ResistAid) on the antibody response to the pneumococcal vaccine in 45 healthy adults. The arabinogalactan group showed a significantly greater IgG antibody response in subtypes 18C and 23F compared to placebo, indicating enhanced immunity.
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance
The study investigates the multi-target mode of action of silver against antibiotic-resistant Staphylococcus aureus. It identifies 38 Ag+-binding proteins and demonstrates that silver can inhibit key bacterial enzymes, enhancing the efficacy of conventional antibiotics and resensitizing MRSA to antibiotics.
Effect of galactose and sugar substitutes on blood insulin levels in normal and obese individuals.
Double-blind randomized study with 18 male patients testing the effects of galactose, arabinogalactan, sodium saccharin, and methyl cellulose on blood glucose, galactose, and insulin levels. None of the substances altered plasma insulin or glucose levels, suggesting sweet taste does not induce insulin secretion through neurogenic pathways.